seattle mariners nike 2023 city connect replica jersey - royal Patients with signs and symptoms of MR with severely depressed systolic function (ie, EF <30%) can present a difficult diagnostic and management dilemma. It can be difficult to establish whether the primary problem is that of MR causing LV dilatation and dysfunction or a cardiomyopathic process leading to secondary (ie, “functional”) MR.
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The ACE inhibitor did not decrease either blood pressure or LVH; however, it significantly decreased LV collagen from 13.3±0.9 to 9.6±0.6 μg/mg dry wt ( P <0.006), and this effect was blocked by the mAb (12.1±0.6; P <0.034, ACE inhibitor versus ACE inhibitor+mAb).
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In the absence of symptoms, LV dysfunction has been a key factor for consideration for surgery because the so-called 'normal' EF is actually low in severe MR due to significant retrograde flow to LA. This low EF can cause significant impairment in recovery after surgical correction.
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